COSTEP-I is It is a Macrolide. It binds to the 50S sub unit of bacterial ribosome and inhibits translocation.ie: they interfere with the transfer of the newly formed peptide chain from the A site to the P site and fails to expose the A site .So that A site is unable to bind with the next aminoacyl tRNA complex. This leads to premature termination of amino acid chain and there by inhibits protein synthesis Absorption: It is well absorbed after oral administration. Distribution: It is very widely distributed in the body as protein bound form. Metabolism: Drug is metabolized in the liver. Excretion: The drug is excreted through urine and small amount through bile and breast milk.
It is a Macrolide.
Pharmacokinetics: Absorption: It is well absorbed after oral administration. Distribution: It is very widely distributed in the body as protein bound form. Metabolism: Drug is metabolized in the liver. Excretion: The drug is excreted through urine and small amount through bile and breast milk.
Pregnancy Information: ['Contra indicated']
Overdose Effect: Give supportive measures and sumptomatic treatment.
Missed Dosage: Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule.Do not double the dose.