CHLORPROMAZINE is Aliphatic phenothiazine derivative, First-Generation Antipsychotic(typical), anticholinergic, antidopaminergic, antihistaminic, and antiadrenergic, Tranquilizer, Antiemetic Antipsychotic action: Chlorpromazine binds to the dopamine receptor (D1, D2, D3 &D4).It exerts its antipsychotic activity by blocking the dopamine projections in the limbic system and in mesocortical area. Peripherally and centrally it acts as a competitive Dopamine antagonist. Chlorpromazine also produces alpha adrenergic blocking activity and anticholinergic activity. It also produces weak H1 antihistaminic activity and anti serotonin activity. Absorption: It is absorbed after oral administration. Absorption rate varies with route of administration. Distribution: It is distributed widely in the body in protein bound form. Metabolism: It is metabolised in the liver and produce both active and inactive metabolites. Excretion: It is excreted mainly through urine. Small amount of drug is excreted through faeces and breast milk.
Aliphatic phenothiazine derivative, First-Generation Antipsychotic(typical), anticholinergic, antidopaminergic, antihistaminic, and antiadrenergic, Tranquilizer, Antiemetic
Pharmacokinetics: Absorption: It is absorbed after oral administration. Absorption rate varies with route of administration. Distribution: It is distributed widely in the body in protein bound form. Metabolism: It is metabolised in the liver and produce both active and inactive metabolites. Excretion: It is excreted mainly through urine. Small amount of drug is excreted through faeces and breast milk.
Pregnancy Information: ['Contraindicated']
Overdose Effect: Give supportive measures and symptomatic treatment.
Missed Dosage: Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose.