CETROTIDE is GnRH antagonist, A systemic female anti infertility agent. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Cetrorelix competes with natural GnRH for binding to membrane receptors on pituitary cells and thus controls the release of LH and FSH in a dose-dependent manner. Cetrorelix blocks the effects of the naturally occurring gonadotropin-releasing hormone (GnRH). GnRH controls the release of another hormone, luteinizing hormone (LH), which induces ovulation (release of an egg from the ovary) during the menstrual cycle. During hormone treatment for ovarian stimulation, premature ovulation may lead to eggs that are not suitable for fertilization. Cetrorelix blocks this undesirable premature ovulation. Absorption:It is rapidly absorbed after subcutaneous administration.Distribution:It is distributed mainly in protein bound form. Metabolism:It undergoes hepatic metabolism.Excretion:Drug and its metabolites are excreted mainly in urine and bile.
GnRH antagonist, A systemic female anti infertility agent.
Pharmacokinetics: Absorption:It is rapidly absorbed after subcutaneous administration.Distribution:It is distributed mainly in protein bound form. Metabolism:It undergoes hepatic metabolism.Excretion:Drug and its metabolites are excreted mainly in urine and bile.
Pregnancy Information: ['Contraindicated']
Overdose Effect: Give supportie measures and symptomatic treatment.
Missed Dosage: Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule.Do not double the dose.