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CEFEST 500 mg - Vial

CEFEST is Third Generation cephalosporin Parenteral antibiotic. Cefotaxime is a 3rd generation cephalosporin which exerts its bactericidal action against both gram positive & aerobic gram negative organisms by inhibiting bacterial cell wall synthesis. Cefotaxime inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefotaxime Absorption: Orally not well absorbed & should be given parenterally, Distribution: widely distributed, & good CSF penetration, Metabolism: A portion of it is deacetylated in the body in to an active metabolite desacetylcefotaxime, Excretion: Excreted mainly through urine & small amount is seen in breast milk.

Third Generation cephalosporin Parenteral antibiotic.

Pharmacokinetics: Absorption: Orally not well absorbed & should be given parenterally, Distribution: widely distributed, & good CSF penetration, Metabolism: A portion of it is deacetylated in the body in to an active metabolite desacetylcefotaxime, Excretion: Excreted mainly through urine & small amount is seen in breast milk.

Pregnancy Information: ['Use with caution.']

Overdose Effect: Symptoms of over dosage include neuromuscular disorders & some times seizure may get precipitated. Treatment includes removal of drug from the body by dialysis & supportive measures

Missed Dosage: Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose.