CEFADIN is First Generation cephalosporin antibiotic Cefazolin is a 1st generation cephalosporin which exerts its bactericidal action against both gram positive & gram negative organisms by inhibiting bacterial cell wall synthesis. Cefazolin inhibits transpeptidase & thus prevents cross linking of bacterial cell wall. Transpeptidase & associated proteins constitute various types of specific binding proteins which have affinity for cephalosporins like Cefazolin Absorption: Orally not well absorbed & should be given parenterally, Distribution: widely distributed, Metabolism: Not metabolized, Excretion: Excreted mainly through urine & small amount is seen in breast milk.
First Generation cephalosporin antibiotic
Pharmacokinetics: Absorption: Orally not well absorbed & should be given parenterally, Distribution: widely distributed, Metabolism: Not metabolized, Excretion: Excreted mainly through urine & small amount is seen in breast milk.
Pregnancy Information: ['Use with caution.']
Overdose Effect: Symptoms of over dosage include neuromuscular disorders & some times seizure may get precipitated. Treatment includes removal of drug from the body by dialysis & supportive measures
Missed Dosage: Take the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose.