CARBAMAX is Tricyclic anticonvulsant , iminostilbene derivative, anticonvulsant , in trigeminal neuralgia. Carbamazepine prolongs the inactivated state of voltage sensitive neuronal sodium ion channel either by increasing the efflux or decreasing the influx of sodium ion across the cell membrane and inhibits the high frequency discharge. Absorption: Carbamazepine is slowly absorbed after oral administration. Distribution: It is distributed widely in the body in protein bound form. Metabolism: It is metabolised in the liver by oxidation to an active metabolite 10, 11 Epoxycarbamazepine. Excretion: Excreted mainly in urine and small amount in faeces.
Tricyclic anticonvulsant , iminostilbene derivative, anticonvulsant , in trigeminal neuralgia.
Pharmacokinetics: Absorption: Carbamazepine is slowly absorbed after oral administration. Distribution: It is distributed widely in the body in protein bound form. Metabolism: It is metabolised in the liver by oxidation to an active metabolite 10, 11 Epoxycarbamazepine. Excretion: Excreted mainly in urine and small amount in faeces.
Pregnancy Information: ['Contraindicated']
Overdose Effect: Give supportive measures and symptomatic treatment. Gastric lavage can be done to remove the drug from the body. To reduce the absorption of the drug activated charcoal can be given to the patient. Maintain fluid and electrolyte balance. Seizure should be controlled by administration of parenteral Diazepam or Barbiturates but they may exacerbate respiratory depression.
Missed Dosage: Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.